Everything about ceesdekker.net

Utilizing one-molecule optical and AFM imaging and pressure-spectroscopy strategies, we seek to unravel the mechanistic components of the framework and dynamics of chromosomes. Our analysis interests include things like:

But how can morality, the dignity with the human being, my experience with the that means of existence, follow within the motion of atoms? A purely naturalistic viewpoint fails here; a Christian standpoint, I believe, is a way more realistic method to interpret these components of fact.’

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Deposition and atomic power microscopy of person phthalocyanine polymers among nanofabricated electrodes

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Microbiology has only existed for a century, given that we started to examine micro-organisms far more severely. I assumed nanobiology was an ideal phrase, for the reason that all molecular biological pertinent interactions happen for the nanoscale: a protein is some nanometres in size, DNA is two nm thick.’

‘Initially we looked at Organic systems using a Bodily perspective and acted on the basis on the applications we knew. It took a several years right before we started Functioning additional on the massive biological problems. I then started to simply call it nanobiology, a term that did not exist at the time.

Nanopores symbolize a chic and adaptable Device to measure single molecules. We study novel detection modes with strong-state nanopores in addition to numerous methods to measure proteins with nanopores. Tasks encompass the following:

2003, demonstrated the main biosensors built away from a carbon nanotube; solved the construction and mechanism of DNA maintenance proteins; ceesdekker and discovery of a completely new strategy for fabricating reliable-state nanopores for DNA translocation

Quite cool, but that wasn’t actually wherever my curiosity lay. I planned to pioneer And that i had the feeling which was now not feasible, since the most attention-grabbing fundamental insights had by now been uncovered. But my industry had produced quite a few thrilling new equipment to evaluate unique molecules. I decided that I desired to implement this to biology, to have a look at it from the Actual physical point of view.’

Screening pseudotopological and nontopological products for SMC-driven DNA loop extrusion in opposition to roadblock-traversal experiments

Several new phenomena were learned, and he and his analysis team proven a number one placement Within this industry of analysis. Dekker and his investigate group discovered new physics of nanotubes and also explored the feasibility of molecular electronics. In 1998, they were the 1st to construct a transistor dependant on just one nanotube molecule.

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 Lastly, I will briefly sketch a few of our Tips to check out the making of artificial cells, particularly our initial measures to ascertain synthetic cell division.

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